Hepatitis in dogs, symptom and diagnosis
ICH is often seen on dog under 1 year old
Infected dogs will die within an hour after the appearance of clinical signs.
Clinical signs at an early period.
Increasing rectum’s temperature (39°C to 41°C), increasing frequency of breathing.
Maybe it’s out of fever, inflammation of tonsil are usually accompanied with sore throat and bronchitis, cough and sputum in the respiratory system.
Lymph node appearing on the neck causes edema under the scalp and neck. Acute hepatitis causes stomachache, petechia and bruise spreads under the skin, nosebleed and venous bleeding.
Jaundice does not occur in an acute period of ICH. But the disease appears in dogs surviving through the acute period of the disease. Hepatitis causes the dog to become bloated by the accumulation of many fluids( Included: serum and blood) or by internal bleeding. The sign of injury central nervous system included: sullen look, disoriented, convulsive, coma or deep coma in the final period. After escaping from fever, the dog is able to recover. The ICH’s complication may lengthen from 5 to 7 days before decreased. Cornea edema and membrane inflammation of the eye appears when clinical symptoms fade away. Mortality rate is usually from 10% to 30% , highest in small dogs.
Diagnosis of hepatitis.
Diagnose serum for ICH early. On seriously affected dog see that the cell injury is at a serious degree ( increased ALT and AST). Proteinuria is very common, leukopenia lengthens during the fever process. The degree of increasing leucopenia changed, same to the degree of danger of the disease.
Protein assesses of the injury dgree to the kidneys caused by virus. It can be detected on urine analysis, because alcohol concentration is greater than 50mg/dl. In the first period, the increasing permeability of glomerular is caused by the virus existing there. In final period, These dogs will gets hypoglycemia.
Test results show that Clinical diagnosing with ICH is a prime method. before it gets a death, perform serological tests, analyze virus by immunofluorescence method, virus staining in diseased tissue. Inspect serum includes viral neutralization reaction, stop indirect hemoglobin, combine complement, antigen reaction, antibody and ELISA.